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Chenodeoxycholic acid (CDCA) is mainly used to reduce bile cholesterol saturation, the vast majority of patients taking CDCA (when CDCA for bile salt in 70%), recovery of lipid micelles, cholesterol is not saturated, so that the stones in the solubility of cholesterol and fall off. Large doses of CDCA (10 to 15mg/kg per day) can prevent the synthesis of cholesterol and increase bile secretion in patients with cholelithiasis, but the secretion of bile salts and phospholipids remains unchanged.