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Ursodeoxycholic Acid

Ursodeoxycholic Acid CAS:128-13-2

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  Ursodeoxycholic acid is a white powder, odorless and bitter. Mp 200-204 C. Soluble in ethanol and acetic acid, dissolved in sodium hydroxide solution, insoluble in chloroform. UDCA is a isomer of CDCA, whose dissolution is stronger than CDCA, without diarrhea and liver toxicity. UDCA can reduce cholesterol absorption, reduce cholesterol synthesis and cholesterol content in bile. In addition, UDCA can also reduce concanavalin A binding fragments, which can promote the formation of bile crystals, thereby preventing the formation of stones. Combined use of UDCA and CDCA can enhance the dissolution of individual stones and reduce side effects. The combination of these two methods is mainly used for cholesterol gallstone in the gallbladder. When the density of gallstones and bile is equal to or the CT value of gallstone is less than 75 units, the dissolution rate of UDCA is faster. The number of peripheral platelets can be increased after the use of this product in patients with cholelithiasis.

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